Target expression details
Target General Information | |||||
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Target ID | T73495 | ||||
Target Name | Glutamate receptor ionotropic kainate 1 | ||||
Synonyms | EAA3; Excitatory amino acid receptor 3; GluR-5; GluR5; GluR5 kainate receptor; Glutamate receptor 5; GRIK1 | ||||
Target Type | Successful | ||||
Gene Name | GRIK1 | ||||
Biochemical Class | Glutamate-gated ion channel | ||||
UniProt ID | GRIK1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Epilepsy | ||||
Example drug | Topiramate | Approved | [536756], [541929], [551871], [1572592] | ||
Tissue | Peritumoral cortex tissue | ||||
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 541929 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6849). | ||||
Ref 536756 | Use of second-generation antiepileptic drugs in the pediatric population. Paediatr Drugs. 2008;10(4):217-54. |
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