Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T75498 | ||||
| Target Name | Quinone reductase 2 | ||||
| Synonyms | NAD(P)H qui oxidoreductase 2; NRH:qui oxidoreductase 2; NRH:quinone oxidoreductase 2; QR2; Qui reductase 2; Quinone oxidoreductase 2; Quinone reductase 2; NQO2 | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | NQO2 | ||||
| Biochemical Class | Oxidoreductases acting on diphenols as donors | ||||
| UniProt ID | NQO2_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Breast cancer | ||||
| Example drug | NSC-645809 | Phase 2 | [531934], [1572592] | ||
| Tissue | Breast tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.13 Z-score: -0.34 P-value: 1.56E-10 |
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| Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: 1.23E-03 Z-score: 3.29E-03 P-value: 3.31E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
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| Disease | Epilepsy | ||||
| Tissue | Peritumoral cortex tissue | ||||
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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