Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T78692 | ||||
| Target Name | ATP-sensitive potassium channel | ||||
| Synonyms | CIR; Cardiac inward rectifier; GIRK4; Heart KATP channel; Inward rectifier K+ channel Kir3.4; KATP channel; KATP-1; Potassium channel, inwardly rectifying, subfamily J, member 5; KCNJ5 | ||||
| Target Type | Research | ||||
| Gene Name | ABCC8 | ||||
| Biochemical Class | Inward rectifier K(+) channel | ||||
| UniProt ID | ABCC8_HUMAN||ABCC9_HUMAN||KCJ11_HUMAN||KCNJ8_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Chronic obstructive pulmonary disease | ||||
| Tissue | Lung tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.08 Z-score: 0.47 P-value: 1.18E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Chronic obstructive pulmonary disease | ||||
| Tissue | Small airway epithelium | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.08 Z-score: 0.43 P-value: 1.73E-03 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Multiple sclerosis | ||||
| Tissue | Spinal cord | ||||
| Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: -1.28E-03 Z-score: -0.01 P-value: 7.95E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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