Target General Information
Target ID T86271
Target Name Small conductance calcium-activated potassium channel KCa2.2
Synonyms KCNN2
Target Type Clinical Trial
Gene Name KCNN2
UniProt ID KCNN2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Myeloma
Example drug zoxazolamine Terminated [539473], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.41E-02
Z-score: 0.15
P-value: 5.17E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 539473(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2327).
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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