Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T92777 | ||||
| Target Name | Maltase-glucoamylase intestinal | ||||
| Synonyms | Alpha-glucosidase; MGAM | ||||
| Target Type | Successful | ||||
| Gene Name | MGAM | ||||
| Biochemical Class | Glycosylases | ||||
| UniProt ID | MGA_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Type 2 diabetes | ||||
| Example drug | Miglitol | Approved | [1], [2], [3] | ||
| Tissue | Liver tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.02 Z-score: -0.24 P-value: 4.59E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Reference | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4842). | ||||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| REF 3 | NCBI GEO: archive for functional genomics data sets--update. | ||||
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