Target General Information
Target ID T98062
Target Name Glycogen phosphorylase muscle form
Synonyms Glycogen phosphorylase b; Muscle glycogen phosphorylase; PYGM
Target Type Discontinued
Gene Name PYGM
Biochemical Class Hexosyltransferase
UniProt ID PYGM_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug JTT-651 Discontinued in Phase 1 [548600], [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.23
Z-score: -0.14
P-value: 2.69E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 548600Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026877)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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