Target Information
Target General Infomation | |||||
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Target ID |
T00335
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Former ID |
TTDR00949
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Target Name |
Elongation factor 1-alpha
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Gene Name |
EEF1A
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Synonyms |
EF-1 alpha; EF-1-alpha-1; EF-Tu; Elongation factor Tu; EEF1A
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Target Type |
Clinical Trial
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Disease | Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10: A00-B99] | ||||
Function |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
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BioChemical Class |
GTP-binding elongation factor family
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UniProt ID | |||||
Sequence |
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL
DKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKK IGYNPDTVAFVPISGWNGDNMLEPSSNMPWFKGWKVTRKDGNASGTTLLEALDCILPPTR PTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALS EALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPV LDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMIPGKPMCVESFSDYPP LGRFAVRDMRQTVAVGVIKAVDKKAGGAGKVTKSAQKAQKAK |
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Drugs and Mode of Action | |||||
References |
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