Target Information
Target General Infomation | |||||
---|---|---|---|---|---|
Target ID |
T23688
|
||||
Former ID |
TTDR00022
|
||||
Target Name |
3-Deoxy-D-manno-octulosonate 8-phosphate synthase
|
||||
Gene Name |
kdsA
|
||||
Synonyms |
2-dehydro-3-deoxyphosphooctonate aldolase; 3-Deoxy-d-manno-2-octulosonate-8-phosphate synthase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO8-P synthase; KDO8P synthase; KDO8PS; KDOP synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase; kdsA
|
||||
Target Type |
Research
|
||||
Function |
Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.
|
||||
BioChemical Class |
Alkyl aryl transferase
|
||||
UniProt ID | |||||
EC Number |
EC 2.5.1.55
|
||||
Sequence |
MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDK
ANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLAR QTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVD MLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEA HPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK |
||||
Inhibitor | 1-Deoxy-Ribofuranose-5'-Phosphate | Drug Info | [551393] | ||
2-(Phosphonooxy)Butanoic Acid | Drug Info | [551391] | |||
2-Phosphoglyceric Acid | Drug Info | [551393] | |||
3-Fluoro-2-(Phosphonooxy)Propanoic Acid | Drug Info | [551393] | |||
Arabinose-5-Phosphate | Drug Info | [551393] | |||
Erythose-4-Phosphate | Drug Info | [551393] | |||
Phosphoenolpyruvate | Drug Info | [551393] | |||
Ribose-5-Phosphate | Drug Info | [551393] | |||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.