Target Information
Target General Infomation | |||||
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Target ID |
T56143
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Former ID |
TTDI00075
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Target Name |
G protein-coupled receptor 35
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Gene Name |
GPR35
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Synonyms |
Gprotein coupled receptor 35; KYNA receptor; Kynurenic acid receptor; GPR35
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Target Type |
Research
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Function |
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
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BioChemical Class |
GPCR rhodopsin
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UniProt ID | |||||
Sequence |
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS QDSLCVTLA |
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Pathways | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
References |
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