Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T66350
|
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| Former ID |
TTDR00036
|
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| Target Name |
Ras-related protein Rab-9A
|
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| Gene Name |
RAB9A
|
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| Synonyms |
RAB9A
|
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| Target Type |
Successful
|
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| Disease | Fungal infections [ICD9: 110-118; ICD10: B35-B49] | ||||
| Function |
Involved in the transport of proteins between the endosomes and the trans Golgi network.
|
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| BioChemical Class |
Small GTPase superfamily
|
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| UniProt ID | |||||
| Sequence |
MAGKSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQI
WDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFV ILGNKIDISERQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSD HLIQTDTVNLHRKPKPSSSCC |
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| Drugs and Mode of Action | |||||
| Drug(s) | Benzoic Acid | Drug Info | Approved | Fungal infections | [1], [2] |
| Inhibitor | Benzoic Acid | Drug Info | [3] | ||
| Guanosine-5'-Diphosphate | Drug Info | [3] | |||
| Pathways | |||||
| KEGG Pathway | Measles | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4565). | ||||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
| REF 3 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | ||||
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