Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T79589
|
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| Former ID |
TTDR00304
|
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| Target Name |
Enoyl-[acyl-carrier-protein] reductase [NADH] 2
|
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| Gene Name |
fabI2
|
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| Synonyms |
Enoyl-ACP reductase II; NADH-dependent enoyl-ACP reductase 2; fabI2
|
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| Target Type |
Research
|
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| BioChemical Class |
Oxidoreductases acting on CH-CH group of donors
|
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| UniProt ID | |||||
| EC Number |
EC 1.3.1.9
|
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| Sequence |
MNGLMNGKRGLIMGVANSHSIAWGIAKSLAAQGAELAFTYQGEALGKRVKPLAAEVNSDF
LLPCDVEDIGSVDAVVDAIKERWGKLDFVVHAIGFSDKNELKGLYADTTRDNFSRTMVIS CFSFTEIAKRAAELMSEGGTMLTLTYGGSMRVMPNYNVMGVAKAALEASVRYLAADYGSR GIRVNAISAGPIRTLAGAGISDARAMLSWQQKNSPLRRTVTIEDVGSSALYLLSDLSRGV TGEIHYVDSGYNITSMPTLEALRVADAD |
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| Inhibitor | Diazaborines | Drug Info | [1] | ||
| Pathways | |||||
| KEGG Pathway | Fatty acid biosynthesis | ||||
| Biotin metabolism | |||||
| Metabolic pathways | |||||
| Fatty acid metabolism | |||||
| References | |||||
| REF 1 | Lipid biosynthesis as a target for antibacterial agents. Prog Lipid Res. 2001 Nov;40(6):467-97. | ||||
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