Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- Cyclin E | (2,6-Bis-trifluoromethyl-quinazolin-4-yl)-tert-butyl-amine | Drug Info |
| CDK2 --- Cyclin E | N*6*-Biphenyl-4-ylmethyl-9-isopropyl-N*2*,N*2*-bis-(2-methoxy-ethyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-(2-hydroxy-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-(3-methyl-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | N-[5-(4-Ethyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- GSK3 | N-(6-(furan-2-yl)-1H-indazol-3-yl)cyclopropanecarboxamide | Drug Info |
| CAII --- CAI | 6-(Nonafluorobutane-1-sulfonylamino)-benzothiazole-2-sulfonic acid amide | Drug Info |
| CDK4 --- Cyclin E | 1-Morpholin-4-yl-3-{4-oxo-3-[5-(piperidine-1-carbonyl)-thiophen-2-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-urea | Drug Info |
| CAII --- CAI | 6-[2-(4-Sulfamoyl-phenyl)-ethoxycarbamoyl]-pyridine-2-carboxylic acid | Drug Info |
| Ckit --- BRaf | 4-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carbamoyl)thiazol-4-ylamino)methyl)-N-methylpicolinamide | Drug Info |
| CAII --- CAI | (3aS,3bR,7aS,8aR)-N-(aminosulfonyl)-2,2,5,5-tetramethyltetrahydro-8aH-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxine-8a-carboxamide | Drug Info |
| COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1,5-diphenyl-1H-pyrazole | Drug Info |
| CAII --- CAI | ([2-(Carboxymethyl-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-ethyl]-{[2-(4-sulfamoyl-phenyl)-ethylcarbamoyl]-methyl}-amino)-acetic acid; compound with Zn complex | Drug Info |
| COX2 --- 5LOX | 1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-hexan-1-one | Drug Info |
| CAII --- CAI | (S)-2-(4-Chloro-3-sulfamoyl-benzoylamino)-3-methyl-butyric acid | Drug Info |
| COX2 --- 5LOX | (7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-thiophen-2-yl-methanone | Drug Info |
| CAII --- CAI | [Carboxymethyl-(4-sulfamoyl-benzyloxycarbonylmethyl)-amino]-acetic acid | Drug Info |
| CSrc --- CABL | N-(5-(3-chlorobenzylthio)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide | Drug Info |
| CAII --- CAI | 1-[(2-Fluoro-4-sulfamoyl-phenylcarbamoyl)-methyl]-2,4,6-trimethyl-pyridinium; perchlorate | Drug Info |
| CSrc --- CABL | 1-(2-bromo-2-phenylethyl)-6-(methylthio)-N-phenethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | 4-{2-[(heptadecafluorooctyl)sulfonyl]hydrazino}benzenesulfonamide | Drug Info |
| CSrc --- CABL | Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-amide | Drug Info |
| CAII --- CAI | {{2-[2-(2-{Carboxymethyl-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-ethoxy)-ethoxy]-ethyl}-[(2-chloro-4-sulfamoyl-phenylcarbamoyl)-methyl]-amino}-acetic acid | Drug Info |
| CSrc --- CABL | 1-(2-chloro-2-(4-fluorophenyl)ethyl)-N-(3-fluorophenyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| CAII --- CAI | N,N-dialkylthio-carbonylsulfenylamino derivative | Drug Info |
| CSrc --- CABL | ((4-(2-(cis-4-aminocyclohexyl)-9-ethyl-9H-purin-6-ylamino)phenyl)(hydroxy)phosphoryl)methylphosphonic acid | Drug Info |
| CAII --- CAI | 3-(4-Sulfamoyl-benzoylamino)-propionic acid | Drug Info |
| CSrc --- CD221 | N'-({2'-[(4-Fluorobenzyl)oxy][1,1'-biphenyl]-4-yl}carbonyl)-2-(1H-indol-3-yl)-2-oxoacetohydrazide | Drug Info |
| CAII --- CAI | N-(4-hydroxyphenyl)sulfamide | Drug Info |
| DHFR --- MMP-9 | methotrexate gamma-L-phenylalaninehydroxamic acid | Drug Info |
| CAII --- CAI | (R)-4-((8S,10S,12S,14R,15R,17S)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid 2-(4-sulfamoyl-phenyl)-ethyl ester | Drug Info |
| DHFR --- TYMS | SID536361 | Drug Info |
| CAII --- CAI | 2,3,4,5,6-Pentafluoro-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-benzamide | Drug Info |
| EGFR --- HER2 | But-2-enoic acid [4-(3-bromo-phenylamino)-quinazolin-6-yl]-amide | Drug Info |
| CAII --- CAI | 2-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Drug Info |
| EGFR --- Src | Acetic acid 2-(4-acetoxy-1-methyl-3-phenylcarbamoyl-1H-indol-2-yldisulfanyl)-1-methyl-3-phenylcarbamoyl-1H-indol-4-yl ester | Drug Info |
| CAII --- CAI | 4-Chloro-6-pentafluorobenzenesulfonylamino-benzene-1,3-disulfonic acid diamide | Drug Info |
| EGFR3 --- CSrc | methyl 4-{1-methyl-2-[1-methyl-3-(4-methyloxycarbonylbenzoyl)-1H-2-indolyldisulfanyl]-1H-3-indolylcarbonyl}benzoate | Drug Info |
| CAII --- CAI | 6-(2-Bromo-4-sulfamoyl-phenylcarbamoyl)-pyridine-2-carboxylic acid | Drug Info |
| EGFR3 --- HER2 | 6,7-dimethoxy-4-(p-tolylamino)quinoline-3-carbonitrile | Drug Info |
| CAII --- CAI | [(2-Hydroxy-phenyl)-(2-{(2-hydroxy-phenyl)-[(4-sulfamoyl-benzylcarbamoyl)-methyl]-amino}-ethyl)-amino]-acetic acid | Drug Info |
| 5HT1a --- SERT | 1-phenyl-3-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[(4S,6R)-2-methyl-4-(4-trifluoromethyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-nitrophenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-chlorophenyl)piperazin-1-yl)-1-phenylpropan-1-one | Drug Info |
| 5LOX --- HRH1 | [3-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-furan-2-yl)-1-methyl-prop-2-ynyl]-N-hydroxyurea | Drug Info |
| ADRA1A --- HRH1 | 4-[(4-Fluorophenyl)methyl]-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | SID56463056 | Drug Info |
| ADRA1A --- HRH1 | 4-[(4-Chlorophenyl)methyl]-2-{1-[2-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)ethyl]hexahydro-1H-azepin-4-yl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 2-Ethyl-10-piperazin-1-yl-4H-3-thia-4,9-diaza-benzo[f]azulene | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.