| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T49639 | ||||
| Target Name | Heat shock protein 70 | ||||
| Target Type | Clinical Trial |
||||
| Drug Potency against Target | Adenosine triphosphate | Drug Info | IC50 = 3370 nM | [531262] | |
| NSC-119910 | Drug Info | IC50 = 9850 nM | [531262] | ||
| ELLAGIC ACID | Drug Info | IC50 = 760 nM | [531262] | ||
| NSC-119911 | Drug Info | IC50 = 332 nM | [531262] | ||
| NSC-119913 | Drug Info | IC50 = 634 nM | [531262] | ||
| References | |||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
| Ref 531262 | Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). | ||||
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