Target Validation Information
Target ID T15352
Target Name HIV reverse transcriptase
Target Type
Successful
Drug Potency against Target Stavudine Drug Info EC50 = 9 nM [1]
Didanosine Drug Info EC50 = 10 nM [1]
Abacavir Drug Info EC50 = 230 nM [1]
Zidovudine Drug Info EC50 = 25 nM [1]
Zalcitabine Drug Info EC50 = 160 nM [1]
References
REF 1GABA(A) receptor ligands and their therapeutic potentials. Curr Top Med Chem. 2002 Aug;2(8):817-32.

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