| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T50912 | ||||
| Target Name | T-lymphocyte activation antigen CD86 | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Abatacept | Drug Info | Kd = 6.7 nM | [553226] | |
| References | |||||
| Ref 553226 | Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2). J Immunol. 1996 Feb 1;156(3):1047-54. | ||||
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