| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T55293 | ||||
| Target Name | Integrin alpha-2 | ||||
| Target Type | Clinical Trial |
||||
| Drug Potency against Target | 3-(3-(carbamoyl)benzamido)propanoic acid | Drug Info | IC50 = 9 nM | [528383] | |
| 3-(3-(carbamoyl)benzamido)-3-phenylpropanoic acid | Drug Info | IC50 = 1 nM | [528383] | ||
| 3-(3-(benzamido)-5-nitrobenzamido)propanoic acid | Drug Info | IC50 = 32 nM | [528383] | ||
| References | |||||
| Ref 528383 | Bioorg Med Chem Lett. 2006 Oct 15;16(20):5294-7. Epub 2006 Aug 21.Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists. | ||||
| Ref 528383 | Bioorg Med Chem Lett. 2006 Oct 15;16(20):5294-7. Epub 2006 Aug 21.Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists. | ||||
| Ref 528383 | Bioorg Med Chem Lett. 2006 Oct 15;16(20):5294-7. Epub 2006 Aug 21.Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.