Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T23145 Target Info
Target Name Cholesterol desmolase (CYP11A1)
Synonyms P450(scc); Cytochrome P450(scc); Cytochrome P450 11A1; Cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; CYP11A
Target Type Successful Target
Gene Name CYP11A1
Biochemical Class Paired donor oxygen oxidoreductase
UniProt ID
CP11A_HUMAN
Co-Targets of This Target  Top
Co-Target Name Aromatase (CYP19A1) Successful Target
UniProt ID CP19A_HUMAN
Gene Name CYP19A1
Synonyms P-450AROM; Estrogen synthetase; Estrogen synthase; Cytochrome P450 19A1; Cytochrome P-450AROM; CYPXIX; CYP19; CYAR; ARO1
Representative Drug(s) Aminoglutethimide Drug Info IC50 = 5.2 nM [1]
References  Top
REF 1 Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19). Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64.

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