Co-Target(s) Information

Content Navigation (  All   None )                                      
Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T29500 Target Info
Target Name Adrenergic receptor alpha-1B (ADRA1B)
Synonyms
Alpha-1B adrenoreceptor; Alpha-1B adrenoceptor; Alpha-1B adrenergic receptor; Alpha 1B-adrenoreceptor; Alpha 1B-adrenoceptor
    Click to Show/Hide
Target Type Successful Target
Gene Name ADRA1B
Biochemical Class GPCR rhodopsin
UniProt ID
ADA1B_HUMAN
Co-Targets of This Target  Top
Co-Target Name Adrenergic receptor Alpha-2 (ADRA2) Successful Target
UniProt ID ADA2A_HUMAN; ADA2B_HUMAN; ADA2C_HUMAN
Gene Name NO-GeName
Synonyms
Alpha-2 adrenergic receptor; Alpha(2)-adrenoceptor
    Click to Show/Hide
Representative Drug(s) MEDETOMIDINE Drug Info EC50 = 3 nM Click to Show More [1]
2 MEDETOMIDINE Drug Info EC50 = 3 nM [1]
Co-Target Name Adrenergic receptor alpha-1A (ADRA1A) Successful Target
UniProt ID ADA1A_HUMAN
Gene Name ADRA1A
Synonyms
Alpha-adrenergic receptor 1c; Alpha-1C adrenergic receptor; Alpha-1A adrenoreceptor; Alpha-1A adrenoceptor; Alpha-1A adrenergic receptor; Alpha adrenergic receptor 1c; Alpha 1A-adrenoreceptor; Alpha 1A-adrenoceptor; ADRA1C
    Click to Show/Hide
Representative Drug(s) Methoxamine Drug Info EC50 = 720 nM [2]
References  Top
REF 1 A structure-activity relationship study of benzylic modifications of 4-[1-(1-naphthyl)ethyl]-1H-imidazoles on alpha 1- and alpha 2-adrenergic recep... J Med Chem. 1994 Jul 22;37(15):2328-33.
REF 2 Alpha-adrenergic agents. 1. Direct-acting alpha 1 agonists related to methoxamine. J Med Chem. 1981 Dec;24(12):1432-7.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.