Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T30687 Target Info
Target Name Glucocorticoid receptor messenger RNA (GCR mRNA)
Synonyms
Nuclear receptor subfamily 3 group C member 1 (mRNA); Glucocorticoid receptor (mRNA); GRL (mRNA); GR (mRNA); Alpha-A (mRNA)
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Target Type Successful Target
Gene Name NR3C1
Biochemical Class mRNA target
UniProt ID
GCR_HUMAN
Co-Targets of This Target  Top
Co-Target Name Progesterone receptor (PGR) Successful Target
UniProt ID PRGR_HUMAN
Gene Name PGR
Synonyms
PR; Nuclear receptor subfamily 3 group C member 3; NR3C3
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Representative Drug(s) ORIC-101 Drug Info IC50 = 21 nM [1]
Co-Target Name Androgen receptor (AR) Successful Target
UniProt ID ANDR_HUMAN
Gene Name AR
Synonyms
Testosterone receptor; Nuclear receptor subfamily 3 group C member 4; NR3C4; Dihydrotestosterone receptor; DHTR
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Representative Drug(s) ORIC-101 Drug Info IC50 = 484 nM [1]
References  Top
REF 1 Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101). J Med Chem. 2018 Sep 13;61(17):7767-84.

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