Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T62945 Target Info
Target Name Voltage-gated calcium channel (Cav)
Target Type Successful Target
Gene Name NO-GeName
Biochemical Class Voltage-gated ion channel
UniProt ID
NOUNIPROTAC
Co-Targets of This Target  Top
Co-Target Name Opioid receptor sigma 1 (OPRS1) Successful Target
UniProt ID SGMR1_HUMAN
Gene Name SIGMAR1
Synonyms
hSigmaR1; Sigma1R; Sigma1-receptor; Sigma non-opioid intracellular receptor 1; Sigma 1-type opioid receptor; SRBP; SR31747-binding protein; SR31747 binding protein 1; SR-BP; SIG-1R; Opioid receptor, sigma 1, isoform 1; OPRS1 protein; Aging-associated gene 8 protein; AAG8
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Representative Drug(s) Eperisone Drug Info Ki = 1.704 nM Click to Show More [1]
2 Tolperisone Drug Info Ki = 5.587 nM [1]
Co-Target Name Adrenergic receptor alpha-2B (ADRA2B) Successful Target
UniProt ID ADA2B_HUMAN
Gene Name ADRA2B
Synonyms
Subtype C2; Alpha-2BAR; Alpha-2B adrenoreceptor; Alpha-2B adrenoceptor; Alpha-2B adrenergic receptor; Alpha-2 adrenergic receptor subtype C2; ADRA2RL1; ADRA2L1
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Representative Drug(s) Tolperisone Drug Info Ki = 456 nM [1]
Co-Target Name Muscarinic acetylcholine receptor M2 (CHRM2) Successful Target
UniProt ID ACM2_HUMAN
Gene Name CHRM2
Synonyms
M2 receptor; CHRM2
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Representative Drug(s) Eperisone Drug Info Ki = 831 nM [1]
References  Top
REF 1 DrugMatrix in vitro pharmacology data. National Toxicology Program

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