Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T79068 | Target Info | |||
| Target Name | Bacterial Fatty acid synthetase I (Bact inhA) | ||||
| Synonyms |
Enoyl-[acyl-carrier-protein] reductase [NADH]; Bacterial InhA
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| Target Type | Successful Target | ||||
| Gene Name | Bact inhA | ||||
| Biochemical Class | CH-CH donor oxidoreductase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Mycobacterium Dihydrofolate reductase (MycB folA) | Co-Target | ||||
| UniProt ID | DYR_MYCTU | |||||
| Gene Name | MycB folA | |||||
| Synonyms |
Mycobacterium dfrA
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| Representative Drug(s) | Isoniazid | Drug Info | Ki = 1 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Mycobacterium tuberculosis dihydrofolate reductase is not a target relevant to the antitubercular activity of isoniazid. Antimicrob Agents Chemother. 2010 Sep;54(9):3776-82. | ||||
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