Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09XQF
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| Former ID |
DAP000011
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| Drug Name |
Isoniazid
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| Synonyms |
Abdizide; Andrazide; Anidrasona; Antimicina; Antituberkulosum; Armacide; Armazid; Armazide; Atcotibine; Azuren; Bacillen; Bacillin; Cedin; Cemidon; Chemiazid; Chemidon; Continazine; Cortinazine; Cotinazin; Cotinizin; Defonin; Dibutin; Diforin; Dinacrin; Ditubin; Ebidene; Eralon; Ertuban; Eutizon; Evalon; Fetefu; Fimalene; HIA; Hidranizil; Hidrasonil; Hidrulta; Hidrun; Hycozid; Hydra; Hydrazid; Hydrazide; Hyozid; Hyzyd; INH; Idrazil; Inah; Inizid; Iscotin; Isidrina; Ismazide; Isobicina; Isocid; Isocidene; Isocotin; Isohydrazide; Isokin; Isolyn; Isonerit; Isonex; Isoniacid; Isoniazida; Isoniazide; Isoniazidum; Isonicazide; Isonicid; Isonico; Isonicotan; Isonicotil; Isonicotinhydrazid; Isonicotinohydrazide; Isonide; Isonidrin; Isonikazid; Isonilex; Isonin; Isonindon; Isonirit; Isoniton; Isonizida; Isonizide; Isotamine; Isotebe; Isotebezid; Isotinyl; Isozid; Isozide; Isozyd; LANIZID; Laniazid; Laniozid; Mybasan; Neoteben; Neoxin; Neumandin; Nevin; Niadrin; Nicazide; Nicetal; Nicizina; Niconyl; Nicotibina; Nicotibine; Nicotisan; Nicozide; Nidaton; Nidrazid; Nikozid; Niplen; Nitadon; Niteban; Nydrazid; Nyscozid; Pelazid; Percin; Phthisen; Pycazide; Pyreazid; Pyricidin; Pyridicin; Pyrizidin; Raumanon; Razide; Retozide; Rimicid; Rimifon; Rimiphone; Rimitsid; Robiselin; Robisellin; Roxifen; Sanohidrazina; Sauterazid; Sauterzid; Stanozide; Tebecid; Tebemid; Tebenic; Tebexin; Tebilon; Tebos; Teebaconin; Tekazin; Tibazide; Tibemid; Tibiazide; Tibinide; Tibison; Tibivis; Tibizide; Tibusan; Tisin; Tisiodrazida; Tizide; Tubazid; Tubazide; Tubeco; Tubecotubercid; Tubercid; Tuberian; Tubicon; Tubilysin; Tubizid; Tubomel; Tyvid; Unicocyde; Unicozyde; Vazadrine; Vederon; Zidafimia; Zinadon; Zonazide; Hid rasonil; Isoco tin; Isoniazid SA; Isozid e; Nidra zid; Rimif on; BP 5015; Bp 5 015; FSR 3; I0138; INHd20; L 1945; Nitebannsc 9659; Preparation 6424; RP 5015; AZT + Isoniazid; Cedin (Aerosol); Dow-Isoniazid; FRS-3; FSR-3; Ido-tebin; In-73; Inh-Burgthal; Isoniazid & EEP; Isoniazid & Propolis; Laniazid (TN); Neo-Tizide; Nydrazid (TN); RP-5015; TB-Phlogin; TB-Razide; TB-Vis; Usaf cb-2; I.A.I; RU-EF-Tb; RY-EF-Tb; I.A.I.
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| Drug Type |
Small molecular drug
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| Indication | Tuberculosis [ICD-11: 1B10-1B1Z; ICD-10: A15-A19, B90] | Approved | [1] | |
| Therapeutic Class |
Antitubercular Agents
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| Company |
Roche Pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C6H7N3O
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| Canonical SMILES |
C1=CN=CC=C1C(=O)NN
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| InChI |
1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
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| InChIKey |
QRXWMOHMRWLFEY-UHFFFAOYSA-N
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| CAS Number |
CAS 54-85-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9266, 75070, 602898, 855769, 3133579, 7647563, 7847412, 7979658, 8145964, 8149391, 8152384, 10321551, 10526641, 11112128, 11335245, 11360484, 11363747, 11366309, 11368871, 11371524, 11373562, 11377033, 11461456, 11466189, 11467309, 11483830, 11485678, 11487923, 11490288, 11491837, 11494667, 12016103, 15321438, 17389848, 22389388, 22400349, 24429259, 24896031, 26611787, 26679247, 26746988, 26746989, 26751504, 29222886, 33726819, 38671754, 38671759, 38671761, 46506039, 47216622
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| ChEBI ID |
CHEBI:6030
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| ADReCS Drug ID | BADD_D01204 | |||
| SuperDrug ATC ID |
J04AC01
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| SuperDrug CAS ID |
cas=000054853
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| Drug Resistance Mutation (DRM) | Top | |||
|---|---|---|---|---|
| DRM | DRM Info | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Fatty acid synthetase I (Bact inhA) | Target Info | Inhibitor | [2], [3], [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8. | |||
| REF 2 | Diversity in enoyl-acyl carrier protein reductases. Cell Mol Life Sci. 2009 May;66(9):1507-17. | |||
| REF 3 | Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents. Curr Drug Targets. 2007 Mar;8(3):399-411. | |||
| REF 4 | Screening for novel antituberculosis agents that are effective against multidrug resistant tuberculosis. Curr Top Med Chem. 2007;7(5):499-507. | |||
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