Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T81100 Target Info
Target Name SLC5A2 messenger RNA (SLC5A2 mRNA)
Synonyms
Solute carrier family 5 member 2 (mRNA); Na(+)/glucose cotransporter 2 (mRNA); Low affinity sodium-glucose cotransporter (mRNA)
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Target Type Successful Target
Gene Name SLC5A2
Biochemical Class mRNA target
UniProt ID
SC5A2_HUMAN
Co-Targets of This Target  Top
Co-Target Name Sodium/glucose cotransporter 1 (SGLT1) Clinical trial Target
UniProt ID SC5A1_HUMAN
Gene Name SLC5A1
Synonyms
Solute carrier family 5 member 1; Na(+)/glucose cotransporter 1; NAGT; High affinity sodium-glucose cotransporter
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Representative Drug(s) Bexagliflozin Drug Info IC50 = 2.3 nM [1]
References  Top
REF 1 C-aryl glucosides substituted at the 4'-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4465-70.

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