Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08HUC
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| Former ID |
DAP000935
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| Drug Name |
Isoetharine
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| Synonyms |
Bronkosol; Dilabron; Etyprenaline; Etyprenalinum; Isoetarin; Isoetarina; Isoetarine; Isoetarinum; Neoisuprel; Isoetharine Hcl; Win 3406; Bronkometer (TN); Bronkosol (TN); Dey-Lute Isoetharine; Isoetarina [INN-Spanish]; Isoetarine (INN); Isoetarinum [INN-Latin]; Isoetharine (USP); Isoetharine HCl S/F; Isoetharine [USAN:BAN]; 3,4-Dihydroxy-alpha-(1-(isopropylamino)propyl)benzyl alcohol; 4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Approved | [1], [2] | |
| Therapeutic Class |
Bronchodilator Agents
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| Structure |
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Download2D MOL |
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| Formula |
C13H21NO3
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| Canonical SMILES |
CCC(C(C1=CC(=C(C=C1)O)O)O)NC(C)C
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| InChI |
1S/C13H21NO3/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9/h5-8,10,13-17H,4H2,1-3H3
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| InChIKey |
HUYWAWARQUIQLE-UHFFFAOYSA-N
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| CAS Number |
CAS 530-08-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9265, 4697020, 7979653, 8152380, 11466777, 11467897, 11486413, 15464911, 29222881, 46505384, 47206468, 47440442, 47440443, 47515493, 47810942, 48110635, 49698628, 50064866, 50105269, 50105270, 50398387, 57321982, 85209740, 85788070, 90341304, 103821442, 104304445, 117616915, 123094734, 124749905, 124883527, 124883528, 124883529, 125823582, 128117044, 134224968, 134338210, 134976121, 137087779, 137619493, 160963569, 178103780, 179225230, 223440046, 226439137, 249966774, 252632237
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| ChEBI ID |
CHEBI:6005
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| SuperDrug ATC ID |
R03AC07; R03CC06
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| SuperDrug CAS ID |
cas=000530085
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor beta-2 (ADRB2) | Target Info | Modulator | [3] |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Endocytosis | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Salivary secretion | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Beta2 adrenergic receptor signaling pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | |||
| Arf6 signaling events | ||||
| Reactome | Adrenoceptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Vitamin D Receptor Pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7205). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 086711. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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