Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0LK9N
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| Former ID |
DIB000503
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| Drug Name |
Fradafiban
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| Synonyms |
BIBL-12; BIBU-52; BIBV-52; BIBW-103; BIBW-98
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| Drug Type |
Small molecular drug
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| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Terminated | [1] | |
| Company |
Boehringer Ingelheim Corp
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| Structure |
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Download2D MOL |
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| Formula |
C20H21N3O4
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| Canonical SMILES |
C1C(C(=O)NC1COC2=CC=C(C=C2)C3=CC=C(C=C3)C(=N)N)CC(=O)O
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| InChI |
1S/C20H21N3O4/c21-19(22)14-3-1-12(2-4-14)13-5-7-17(8-6-13)27-11-16-9-15(10-18(24)25)20(26)23-16/h1-8,15-16H,9-11H2,(H3,21,22)(H,23,26)(H,24,25)/t15-,16-/m0/s1
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| InChIKey |
IKZACQMAVUIGPY-HOTGVXAUSA-N
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| CAS Number |
CAS 148396-36-5
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:73266
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005534) | |||
| REF 2 | Profound and sustained inhibition of platelet aggregation by Fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, Lefradafiban, in men. Circulation. 1997Aug 19;96(4):1130-8. | |||
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