Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0N0RU
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| Former ID |
DAP000276
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| Drug Name |
Bexarotene
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| Synonyms |
Bexaroteno; Bexarotenum; Targret; Targretin; Targretyn; Targrexin; Bexarotene [USAN]; Elan brand of bexarotene;Ligand brand of bexarotene; LG 1069; LG100069; LG1069; LG69 compound; LGD 1069; LGD1069; LG-100069; LGD-1069; Targretin (TN); Targretin-gel; Bexarotene (USAN/INN); P-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid; 3-methyl-TTNEB; 4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid; 4-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic acid; 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid; 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid; 4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid; 4-[1-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthaleneyl)vinyl]benzene carboxylic acid; 9RA
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| Drug Type |
Small molecular drug
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| Indication | Cutaneous T-cell lymphoma [ICD-11: 2B01; ICD-10: C84.8; ICD-9: 202.1, 202.2] | Approved | [1], [2] | |
| Therapeutic Class |
Anticancer Agents
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| Company |
Eisai Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H28O2
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| Canonical SMILES |
CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
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| InChI |
1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
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| InChIKey |
NAVMQTYZDKMPEU-UHFFFAOYSA-N
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| CAS Number |
CAS 153559-49-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7978490, 10219206, 11528625, 14876119, 17397261, 43137306, 46509119, 50125754, 50156197, 53790324, 56310969, 56313259, 56313930, 56352964, 57288573, 57333349, 74382986, 85246146, 87550948, 92308910, 93167039, 103274364, 103941130, 104379861, 118314715, 124893632, 124893633, 125341807, 126591248, 126646347, 126667092, 127324027, 127324028, 127324029, 127324030, 127324031, 127324032, 127324033, 128675752, 131300153, 131407703, 134220606, 134337590, 135037531, 135650520, 135692419, 136340346, 136946490, 137002663, 142405765
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| ChEBI ID |
CHEBI:50859
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| ADReCS Drug ID | BADD_D00269 | |||
| SuperDrug ATC ID |
L01XX25
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| SuperDrug CAS ID |
cas=153559490
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2807). | |||
| REF 2 | Emerging drugs in cutaneous T cell lymphoma. Expert Opin Emerg Drugs. 2008 Jun;13(2):345-61. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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