Drug Information
Drug General Information | Top | |||
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Drug ID |
D00BWF
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Former ID |
DNCL001689
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Drug Name |
AGN-XX/YY
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Synonyms |
Rezatomidine
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Drug Type |
Small molecular drug
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Indication | Diabetic nephropathy [ICD-11: GB61.Z] | Phase 2 | [1] | |
Fibromyalgia [ICD-11: MG30.01; ICD-10: M79.7] | Phase 2 | [1] | ||
Company |
ACADIA Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C13H16N2S
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Canonical SMILES |
CC1=C(C(=CC=C1)C(C)C2=CNC(=S)N2)C
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InChI |
1S/C13H16N2S/c1-8-5-4-6-11(9(8)2)10(3)12-7-14-13(16)15-12/h4-7,10H,1-3H3,(H2,14,15,16)/t10-/m0/s1
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InChIKey |
WQXVKEDUCPMRRI-JTQLQIEISA-N
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CAS Number |
CAS 847829-38-3
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Adrenergic receptor alpha-2C (ADRA2C) | Target Info | Agonist | [2] |
KEGG Pathway | cGMP-PKG signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Reactome | Adrenoceptors | |||
Adrenaline signalling through Alpha-2 adrenergic receptor | ||||
Adrenaline,noradrenaline inhibits insulin secretion | ||||
G alpha (i) signalling events | ||||
G alpha (z) signalling events | ||||
Surfactant metabolism | ||||
WikiPathways | Monoamine GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
Platelet Aggregation (Plug Formation) | ||||
Integration of energy metabolism | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of ACADIA Pharmaceuticals. | |||
REF 2 | Patent WO2008058220 A2. |
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