Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00BWZ
|
|||
| Former ID |
DNC011044
|
|||
| Drug Name |
N-(pyridin-3-yl)indoline-1-carboxamide
|
|||
| Synonyms |
CHEMBL42327; N-(pyridin-3-yl)indoline-1-carboxamide; SCHEMBL9035888; 1-(3-pyridylcarbamoyl) indoline; MolPort-003-287-500; BDBM50321878; AKOS001223824; N-(3-Pyridinyl)-2,3-dihydro-1H-indole-1-carboxamide; 2,3-Dihydro-indole-1-carboxylic acid pyridin-3-ylamide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H13N3O
|
|||
| Canonical SMILES |
C1CN(C2=CC=CC=C21)C(=O)NC3=CN=CC=C3
|
|||
| InChI |
1S/C14H13N3O/c18-14(16-12-5-3-8-15-10-12)17-9-7-11-4-1-2-6-13(11)17/h1-6,8,10H,7,9H2,(H,16,18)
|
|||
| InChIKey |
ODXHNGJYIWHPAG-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2C receptor (HTR2C) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorg Med Chem. 2010 Jul 1;18(13):4783-92. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.