Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00DFK
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| Drug Name |
Heteroaryl-azepine derivative 10
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| Synonyms |
PMID26609882-Compound-73
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| Drug Type |
Small molecular drug
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| Company |
ATHERSYS, INC. BENNANI, Youssef, L. ROBARGE, Michael, J. BOM, David, C. VARGA, Norbert TUMEY, Lawrence, NBIOVITRUM AB [SENILSSON BJOERN [SE]
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2C receptor (HTR2C) | Target Info | Agonist | [1] |
| Target's Patent Info | 5-HT 2C receptor (HTR2C) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel serotonin receptor 2 (5-HT2R) agonists and antagonists: a patent review (2004-2014).Expert Opin Ther Pat. 2016;26(1):89-106. | |||
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