Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00EJS
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| Former ID |
DIB018650
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| Drug Name |
5-hydroxyindole
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| Synonyms |
5-Hydroxyindole; 1H-Indol-5-ol; 1953-54-4; INDOL-5-OL; 5-Hydroxy-1H-indole; Hydroxy-5 indole; 5-Indolol; UNII-320UN7XZYN; Hydroxy-5-indole; Hydroxy-5 indole [French]; CCRIS 4422; 5-Hydroxyindole, 97%; EINECS 217-782-6; MFCD00005677; NSC 87503; BRN 0112349; 320UN7XZYN; CHEBI:89649; LMIQERWZRIFWNZ-UHFFFAOYSA-N; NSC-87503; 5-hydroxy-indole; Hydroxy-5 indole [French]; 5-hydroxylindole; 5-hydroxy-indol; 5-hydroxy indole; 3fuh; 5H1; zlchem 359; 5Hydroxy-1H-indole; PubChem7263; 1-H-indol-5-ol; 1H-indol-5-ol.; 4b3c; ACMC-1BQT3; WLN: T56 BMJ GQ
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C8H7NO
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| Canonical SMILES |
C1=CC2=C(C=CN2)C=C1O
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| InChI |
1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
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| InChIKey |
LMIQERWZRIFWNZ-UHFFFAOYSA-N
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| CAS Number |
CAS 1953-54-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
124179, 865950, 1095774, 3133454, 6350007, 8162040, 10512306, 11448789, 15219012, 24724302, 24895561, 25623560, 26683833, 29198238, 29283945, 37361598, 38233547, 39213069, 49747720, 49747721, 49831582, 49984675, 57329232, 79265822, 84981911, 85086789, 87361533, 87570680, 87692414, 92710588, 93620007, 99214837, 99343703, 103578866, 104338805, 117615493, 117653084, 117775957, 124441732, 124784875, 125342142, 126539872, 126575934, 126588512, 126593797, 126607614, 126614900, 126631724, 126637137, 126658095
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| ChEBI ID |
CHEBI:89649
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 3A receptor (HTR3A) | Target Info | Modulator (allosteric modulator) | [2] |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | 5HT3 type receptor mediated signaling pathway | |||
| Reactome | Ligand-gated ion channel transport | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2295). | |||
| REF 2 | The 5-HT3B subunit confers spontaneous channel opening and altered ligand properties of the 5-HT3 receptor. J Biol Chem. 2008 Mar 14;283(11):6826-31. | |||
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