Drug Information
Drug General Information | Top | |||
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Drug ID |
D00FUS
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Former ID |
DNC012394
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Drug Name |
2-(2-Methoxy-phenyl)-1-methyl-ethylamine
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Synonyms |
1-(2-methoxyphenyl)propan-2-amine; 15402-84-3; N-Desmethylmethoxyphenamine; 2-Methoxyamphetamine; o-Methoxyamphetamine; NDMP; 2-(2-Methoxy-phenyl)-1-methyl-ethylamine; CHEMBL16451; Benzeneethanamine, 2-methoxy-alpha-methyl-; Benzeneethanamine,2-methoxy--methyl-; 1-(2-METHOXYPHENYL)-2-PROPYLAMINE; AC1L4MFB; AC1Q57OA; AC1Q45CZ; (d,l)-2-Methoxyamphetamine; Methoxyphenamine, N-desmethyl; SCHEMBL266563; o-Methoxy(phenylisopropyl)amine; AMBZ0414; AC1Q45D0; 2-Methoxy(phenylisopropyl)amine; o-Methoxy-a-methylphenethylamine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H15NO
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Canonical SMILES |
CC(CC1=CC=CC=C1OC)N
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InChI |
1S/C10H15NO/c1-8(11)7-9-5-3-4-6-10(9)12-2/h3-6,8H,7,11H2,1-2H3
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InChIKey |
VBAHFEPKESUPDE-UHFFFAOYSA-N
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CAS Number |
CAS 15402-84-3
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] | |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Calcium signaling pathway | ||||
Gap junction | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
SIDS Susceptibility Pathways | ||||
Serotonin Receptor 2 and STAT3 Signaling | ||||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | 5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogues. J Med Chem. 1986 Feb;29(2):194-9. |
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