Drug Information
Drug General Information | Top | |||
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Drug ID |
D00GOY
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Former ID |
DNC003703
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Drug Name |
VER-3323
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Synonyms |
VER-3323; Lopac-V-1889; CHEMBL309760; 259857-99-3; (2S)-1-(6-bromo-2,3-dihydroindol-1-yl)propan-2-amine; (S)-2-(6-Bromo-2,3-dihydro-indol-1-yl)-1-methyl-ethylamine; SR-01000075153; NCGC00016082-01; AC1O7G7U; Lopac0_000659; GTPL168; SCHEMBL7674586; BDBM50144840; 1H-Indole-1-ethanamine, 6-bromo-2,3-dihydro-alpha-methyl-, (alphaS)-; CCG-204745; NCGC00162213-01; NCGC00162213-02; LS-193647; SR-01000075153-5
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C11H15BrN2
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Canonical SMILES |
CC(CN1CCC2=C1C=C(C=C2)Br)N
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InChI |
1S/C11H15BrN2/c1-8(13)7-14-5-4-9-2-3-10(12)6-11(9)14/h2-3,6,8H,4-5,7,13H2,1H3/t8-/m0/s1
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InChIKey |
QGRQJMXAQYGAKK-QMMMGPOBSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [2] |
5-HT 2B receptor (HTR2B) | Target Info | Inhibitor | [2] | |
5-HT 2C receptor (HTR2C) | Target Info | Inhibitor | [2] | |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Serotonin Receptor 2 and STAT3 Signaling | ||||
SIDS Susceptibility Pathways | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 168). | |||
REF 2 | Indoline derivatives as 5-HT(2C) receptor agonists. Bioorg Med Chem Lett. 2004 May 3;14(9):2367-70. |
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