Drug Information
Drug General Information | Top | |||
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Drug ID |
D00IAK
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Former ID |
DNC008162
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Drug Name |
1,1,1-trifluoro-3-(octylsulfonyl)propan-2-one
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Synonyms |
CHEMBL273139
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C11H19F3O3S
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Canonical SMILES |
CCCCCCCCS(=O)(=O)CC(=O)C(F)(F)F
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InChI |
1S/C11H19F3O3S/c1-2-3-4-5-6-7-8-18(16,17)9-10(15)11(12,13)14/h2-9H2,1H3
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InChIKey |
LGBYSBJDEXOENJ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Fatty acid amide hydrolase (FAAH) | Target Info | Inhibitor | [1] |
Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] | |
BioCyc | Anandamide degradation | |||
KEGG Pathway | Drug metabolism - other enzymes | |||
Metabolic pathways | ||||
Retrograde endocannabinoid signaling | ||||
Panther Pathway | Anandamide degradation | |||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
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REF 1 | Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hy... Bioorg Med Chem. 2008 Feb 15;16(4):2114-30. |
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