Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00JXL
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| Former ID |
DNC012424
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| Drug Name |
N-(4-Phenyl-thiazol-2-yl)-benzamide
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| Synonyms |
CHEMBL60334; N-(4-phenyl-1,3-thiazol-2-yl)benzamide; N-(4-Phenyl-thiazol-2-yl)-benzamide; 14269-45-5; N-(4-phenylthiazol-2-yl)benzamide; Enamine_004302; AC1LF3YD; AC1Q5LQ8; Cambridge id 5149845; Oprea1_016303; Oprea1_462006; Oprea1_007140; CBDivE_004384; SCHEMBL1270375; SCHEMBL18874193; CTK0F0159; DTXSID10353610; MolPort-000-432-183; HMS1406D12; 2-(Benzoylamino)-4-phenylthiazole; ZINC18022084; BDBM50101790; STK972349; STK337540; AKOS002233837; AKOS000478692; MCULE-8414212509; Benzamide, N-(4-phenyl-2-thiazolyl)-; NCGC00262409-01; BAS 0
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C16H12N2OS
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC=CC=C3
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| InChI |
1S/C16H12N2OS/c19-15(13-9-5-2-6-10-13)18-16-17-14(11-20-16)12-7-3-1-4-8-12/h1-11H,(H,17,18,19)
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| InChIKey |
NIRMZOKDACPPER-UHFFFAOYSA-N
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| CAS Number |
CAS 14269-45-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9. | |||
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