Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00QLR
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| Former ID |
DNC008656
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| Drug Name |
(-)-DEBROMOFLUSTRAMINE B
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| Synonyms |
CHEMBL383307; (-)-DEBROMOFLUSTRAMINE B; (-)-DebromoflustramineB; BDBM50241051
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C21H30N2
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| Canonical SMILES |
CC(=CCC12CCN(C1N(C3=CC=CC=C23)CC=C(C)C)C)C
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| InChI |
1S/C21H30N2/c1-16(2)10-12-21-13-15-22(5)20(21)23(14-11-17(3)4)19-9-7-6-8-18(19)21/h6-11,20H,12-15H2,1-5H3/t20-,21+/m1/s1
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| InChIKey |
NUWYFFDZPIGJJO-RTWAWAEBSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinesterase (BCHE) | Target Info | Inhibitor | [1] |
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| WikiPathways | Irinotecan Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors. J Med Chem. 2008 Sep 11;51(17):5271-84. | |||
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