Drug Information
Drug General Information | Top | |||
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Drug ID |
D00QSV
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Former ID |
DNC012388
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Drug Name |
2-(3-Methoxy-phenyl)-1-methyl-ethylamine
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Synonyms |
3-Methoxyamphetamine; 1-(3-methoxyphenyl)propan-2-amine; 17862-85-0; Benzeneethanamine, 3-methoxy-alpha-methyl-; CHEMBL16247; VEJWNIYARKAHFI-UHFFFAOYSA-N; 2-(3-Methoxyphenyl)-1-methylethylamine; 17862-91-8; meta-Methoxyamphetamine; 3-methoxyamphetamine -; 2-(3-Methoxy-phenyl)-1-methyl-ethylamine; AC1L47YE; NCIOpen2_006073; SCHEMBL269071; CTK0H8604; 1-(3-methoxyphenyl)-2-propylamine; BDBM50024211; AKOS000157039; AKOS022196418; MCULE-6670391418; MB01562; 1-(3-Methoxyphenyl)-2-propanamine #; NCI60_042089
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C10H15NO
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Canonical SMILES |
CC(CC1=CC(=CC=C1)OC)N
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InChI |
1S/C10H15NO/c1-8(11)6-9-4-3-5-10(7-9)12-2/h3-5,7-8H,6,11H2,1-2H3
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InChIKey |
VEJWNIYARKAHFI-UHFFFAOYSA-N
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CAS Number |
CAS 17862-85-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
cAMP signaling pathway | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
5HT1 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
G alpha (i) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other | ||||
Serotonin HTR1 Group and FOS Pathway |
References | Top | |||
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REF 1 | 5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogues. J Med Chem. 1986 Feb;29(2):194-9. |
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