Drug Information
Drug General Information | Top | |||
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Drug ID |
D00VHG
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Former ID |
DNC002720
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Drug Name |
Inhibitor Idd 384
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Synonyms |
INHIBITOR IDD 384; CHEMBL240719; [2,6-dimethyl-4-(2-o-tolyl-acetylamino)-benzenesulfonyl]-glycine; I84; AC1L1CKR; BDBM50222612; DB01689; 2-(2,6-dimethyl-4-(2-o-tolylacetamido)phenylsulfonamido)acetic acid; N-[(2,6-dimethyl-4-{[(2-methylphenyl)acetyl]amino}phenyl)sulfonyl]glycine; 2-[[2,6-dimethyl-4-[[2-(2-methylphenyl)acetyl]amino]phenyl]sulfonylamino]acetic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C19H22N2O5S
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Canonical SMILES |
CC1=CC=CC=C1CC(=O)NC2=CC(=C(C(=C2)C)S(=O)(=O)NCC(=O)O)C
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InChI |
1S/C19H22N2O5S/c1-12-6-4-5-7-15(12)10-17(22)21-16-8-13(2)19(14(3)9-16)27(25,26)20-11-18(23)24/h4-9,20H,10-11H2,1-3H3,(H,21,22)(H,23,24)
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InChIKey |
CJKKMQCZOLCXAM-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Aldose reductase (AKR1B1) | Target Info | Inhibitor | [1] |
BioCyc | Methylglyoxal degradation III | |||
Acetone degradation I (to methylglyoxal) | ||||
KEGG Pathway | Pentose and glucuronate interconversions | |||
Fructose and mannose metabolism | ||||
Galactose metabolism | ||||
Glycerolipid metabolism | ||||
Metabolic pathways | ||||
NetPath Pathway | IL1 Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway | ||||
Pathwhiz Pathway | Fructose and Mannose Degradation | |||
Pyruvate Metabolism | ||||
Pterine Biosynthesis | ||||
Glycerolipid Metabolism | ||||
Galactose Metabolism | ||||
WikiPathways | Metapathway biotransformation | |||
Polyol Pathway | ||||
Metabolism of steroid hormones and vitamin D |
References | Top | |||
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REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
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