Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00VJY
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| Former ID |
DIB020592
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| Drug Name |
octanol
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| Synonyms |
1-octanol; Octan-1-ol; octanol; 111-87-5; N-octanol; Capryl alcohol; Octyl alcohol; caprylic alcohol; n-Octyl alcohol; Heptyl carbinol; 1-Hydroxyoctane; Primary octyl alcohol; Alcohol C-8; n-Octan-1-ol; Octilin; Sipol L8; Alfol 8; Lorol 20; Dytol M-83; n-Caprylic alcohol; 1-Octyl alcohol; n-Heptyl carbinol; EPAL 8; octyl-alcohol; Alcohols, C6-12; N-octyl-alcohol; Octyl alcohol, normal-primary; C8 alcohol; Fatty alcohol(C8); Octyl alcohol, primary; Caswell No. 611A; Octyl alcohol (natural); FEMA Number 2800; Lorol C 8-98; n-Capryl alcohol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C8H18O
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| Canonical SMILES |
CCCCCCCCO
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| InChI |
1S/C8H18O/c1-2-3-4-5-6-7-8-9/h9H,2-8H2,1H3
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| InChIKey |
KBPLFHHGFOOTCA-UHFFFAOYSA-N
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| CAS Number |
CAS 111-87-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3023, 4018, 75195, 587845, 822750, 830282, 3135282, 7544276, 8025740, 8142741, 8144978, 8150889, 10504085, 14709457, 15170672, 17389591, 24430804, 24439314, 24847103, 24857646, 24857945, 24862171, 24867772, 24870797, 24890156, 24901178, 24901179, 26752869, 26752870, 30055059, 30955680, 31551468, 32858912, 36655397, 37354943, 48415132, 48417290, 48419137, 48425414, 48426134, 49732778, 49846420, 49856865, 53788048, 57320621, 57646905, 57648362, 57648399, 78684725, 81059635
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| ChEBI ID |
CHEBI:16188
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Connexin-23 (Cx23) | Target Info | Inhibitor | [2] |
| Connexin-25 (Cx25) | Target Info | Inhibitor | [3] | |
| Connexin-30 (Cx30) | Target Info | Inhibitor | [4] | |
| Connexin-32 (Cx32) | Target Info | Inhibitor | [5] | |
| Connexin-45 (Cx45) | Target Info | Inhibitor | [6] | |
| Connexin-59 (Cx59) | Target Info | Inhibitor | [7] | |
| Connexin-62 (Cx62) | Target Info | Inhibitor | [8] | |
| Gap junction alpha-1 protein (GJA1) | Target Info | Inhibitor | [9] | |
| Gap junction alpha-3 protein (Cx46) | Target Info | Inhibitor | [10] | |
| Gap junction alpha-4 protein (Cx37) | Target Info | Inhibitor | [11] | |
| Gap junction alpha-5 protein (Cx40) | Target Info | Inhibitor | [12] | |
| Gap junction alpha-8 protein (Cx50) | Target Info | Inhibitor | [13] | |
| Gap junction beta-2 protein (Cx26) | Target Info | Inhibitor | [14] | |
| Gap junction beta-3 protein (Cx31) | Target Info | Inhibitor | [15] | |
| Gap junction beta-4 protein (Cx30.3) | Target Info | Inhibitor | [16] | |
| Gap junction beta-5 protein (Cx31.1) | Target Info | Inhibitor | [17] | |
| Gap junction delta-2 protein (Cx36) | Target Info | Inhibitor | [18] | |
| Gap junction delta-3 protein (Cx31.9) | Target Info | Inhibitor | [19] | |
| Gap junction delta-4 protein (Cx40.1) | Target Info | Inhibitor | [20] | |
| Gap junction gamma-2 protein (Cx47) | Target Info | Inhibitor | [21] | |
| Gap junction gamma-3 protein (Cx30.2) | Target Info | Inhibitor | [22] | |
| KEGG Pathway | Gap junction | |||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| NetPath Pathway | Wnt Signaling Pathway | |||
| Pathway Interaction Database | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||
| AP-1 transcription factor network | ||||
| N-cadherin signaling events | ||||
| Reactome | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | |||
| Gap junction assembly | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Calcium Regulation in the Cardiac Cell | ||||
| EGF/EGFR Signaling Pathway | ||||
| Wnt Signaling Pathway Netpath | ||||
| Myometrial Relaxation and Contraction Pathways | ||||
| Spinal Cord Injury | ||||
| Corticotropin-releasing hormone | ||||
| Arrhythmogenic Right Ventricular Cardiomyopathy | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| TarBasePathway | ||||
| Gap junction trafficking and regulation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4278). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 714). | |||
| REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 715). | |||
| REF 4 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 717). | |||
| REF 5 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 723). | |||
| REF 6 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 729). | |||
| REF 7 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 733). | |||
| REF 8 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 734). | |||
| REF 9 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 728). | |||
| REF 10 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 730). | |||
| REF 11 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 725). | |||
| REF 12 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 726). | |||
| REF 13 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 732). | |||
| REF 14 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 716). | |||
| REF 15 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 720). | |||
| REF 16 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 719). | |||
| REF 17 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 721). | |||
| REF 18 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 724). | |||
| REF 19 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 722). | |||
| REF 20 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 727). | |||
| REF 21 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 731). | |||
| REF 22 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 718). | |||
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