Target and Pathway |
Top |
Target(s) |
EGFR T790M mutant (EGFR T790M) |
Target Info
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Inhibitor |
[1] |
Janus kinase 1 (JAK-1) |
Target Info
|
Inhibitor |
[1] |
Janus kinase 2 (JAK-2) |
Target Info
|
Inhibitor |
[1] |
Janus kinase 3 (JAK-3) |
Target Info
|
Inhibitor |
[1] |
TYK2 tyrosine kinase (TYK2) |
Target Info
|
Inhibitor |
[1] |
Tyrosine-protein kinase ABL1 (ABL) |
Target Info
|
Inhibitor |
[1] |
Target's Patent Info |
EGFR T790M mutant (EGFR T790M) |
Target's Patent Info
|
[1] |
Janus kinase 1 (JAK-1) |
Target's Patent Info
|
[1] |
Janus kinase 2 (JAK-2) |
Target's Patent Info
|
[1] |
Janus kinase 3 (JAK-3) |
Target's Patent Info
|
[1] |
TYK2 tyrosine kinase (TYK2) |
Target's Patent Info
|
[1] |
Tyrosine-protein kinase ABL1 (ABL) |
Target's Patent Info
|
[1] |
KEGG Pathway
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ErbB signaling pathway
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Ras signaling pathway
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Cell cycle
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Axon guidance
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Neurotrophin signaling pathway
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Pathogenic Escherichia coli infection
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Shigellosis
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Pathways in cancer
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MicroRNAs in cancer
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Chronic myeloid leukemia
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Viral myocarditis
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PI3K-Akt signaling pathway
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Osteoclast differentiation
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Signaling pathways regulating pluripotency of stem cells
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Jak-STAT signaling pathway
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Leishmaniasis
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Toxoplasmosis
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Tuberculosis
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Hepatitis C
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Hepatitis B
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Measles
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Influenza A
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HTLV-I infection
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Herpes simplex infection
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Epstein-Barr virus infection
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Viral carcinogenesis
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Pancreatic cancer
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Chemokine signaling pathway
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Cholinergic synapse
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Prolactin signaling pathway
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Adipocytokine signaling pathway
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Primary immunodeficiency
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NetPath Pathway
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IL2 Signaling Pathway
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Panther Pathway
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Axon guidance mediated by Slit/Robo
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Angiogenesis
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Interferon-gamma signaling pathway
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JAK/STAT signaling pathway
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PDGF signaling pathway
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Inflammation mediated by chemokine and cytokine signaling pathway
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PI3 kinase pathway
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CCKR signaling map ST
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Interleukin signaling pathway
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Pathway Interaction Database
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p73 transcription factor network
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ATM pathway
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Regulation of Telomerase
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Posttranslational regulation of adherens junction stability and dissassembly
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Lissencephaly gene (LIS1) in neuronal migration and development
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PDGFR-beta signaling pathway
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Neurotrophic factor-mediated Trk receptor signaling
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Validated transcriptional targets of TAp63 isoforms
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p53 pathway
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Regulation of retinoblastoma protein
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IL4-mediated signaling events
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IL27-mediated signaling events
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Signaling events mediated by TCPTP
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SHP2 signaling
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IL2-mediated signaling events
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IL2 signaling events mediated by PI3K
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IFN-gamma pathway
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IL6-mediated signaling events
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PDGFR-alpha signaling pathway
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IL2 signaling events mediated by STAT5
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Endothelins
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ErbB4 signaling events
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GMCSF-mediated signaling events
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Signaling events mediated by PTP1B
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IL12-mediated signaling events
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S1P3 pathway
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CXCR4-mediated signaling events
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IL5-mediated signaling events
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ErbB2/ErbB3 signaling events
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IL3-mediated signaling events
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IL23-mediated signaling events
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Signaling events mediated by Stem cell factor receptor (c-Kit)
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EPO signaling pathway
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Notch-mediated HES/HEY network
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CD40/CD40L signaling
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Reactome
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Regulation of actin dynamics for phagocytic cup formation
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CDO in myogenesis
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RHO GTPases Activate WASPs and WAVEs
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HDR through Single Strand Annealing (SSA)
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Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
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Factors involved in megakaryocyte development and platelet production
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Interleukin-6 signaling
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MAPK3 (ERK1) activation
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MAPK1 (ERK2) activation
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GPVI-mediated activation cascade
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ISG15 antiviral mechanism
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Interleukin-7 signaling
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G beta:gamma signalling through PI3Kgamma
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Interleukin-2 signaling
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RAF/MAP kinase cascade
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Interferon gamma signaling
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Regulation of IFNG signaling
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Interferon alpha/beta signaling
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Interleukin receptor SHC signaling
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Regulation of IFNA signaling
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Prolactin receptor signaling
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RMTs methylate histone arginines
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Interleukin-3, 5 and GM-CSF signaling
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RAF activation
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Growth hormone receptor signaling
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WikiPathways
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Apoptosis-related network due to altered Notch3 in ovarian cancer
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Fcgamma receptor (FCGR) dependent phagocytosis
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ATM Signaling Pathway
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Retinoblastoma (RB) in Cancer
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Integrated Pancreatic Cancer Pathway
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Pathogenic Escherichia coli infection
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Regulation of Microtubule Cytoskeleton
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Integrated Breast Cancer Pathway
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Signaling by Robo receptor
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Myogenesis
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Factors involved in megakaryocyte development and platelet production
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Type II interferon signaling (IFNG)
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Interferon type I signaling pathways
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TGF Beta Signaling Pathway
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IL-2 Signaling Pathway
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IL-4 Signaling Pathway
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IL-6 signaling pathway
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TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
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IL-3 Signaling Pathway
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Interleukin-2 signaling
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Interleukin-7 signaling
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JAK/STAT
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PDGF Pathway
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Oncostatin M Signaling Pathway
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Interleukin-11 Signaling Pathway
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Prostate Cancer
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TSLP Signaling Pathway
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IL-9 Signaling Pathway
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Type III interferon signaling
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IL17 signaling pathway
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IL-7 Signaling Pathway
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Leptin signaling pathway
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TSH signaling pathway
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Integrated Cancer pathway
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Interleukin-3, 5 and GM-CSF signaling
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Interferon gamma signaling
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Interferon alpha/beta signaling
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IL-5 Signaling Pathway
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Serotonin Receptor 2 and STAT3 Signaling
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Notch Signaling Pathway
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EPO Receptor Signaling
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EGF/EGFR Signaling Pathway
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Kit receptor signaling pathway
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Mesodermal Commitment Pathway
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Signaling by SCF-KIT
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Prolactin receptor signaling
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Growth hormone receptor signaling
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BDNF signaling pathway
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AGE/RAGE pathway
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