Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01EHP
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| Former ID |
DNC003781
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| Drug Name |
Cyclopentyl-(9-methyl-9H-purin-6-yl)-amine
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| Synonyms |
N6-Cyclopentyl-9-methyladenine; N(6)-Cyclopentyl-9-methyladenine; N-0840; n-cyclopentyl-9-methyl-9h-purin-6-amine; CHEMBL48278; 109292-91-3; Lopac-N-154; 9H-Purin-6-amine,N-cyclopentyl-9-methyl-; AC1Q4XZM; Cyclopentyl-(9-methyl-9H-purin-6-yl)-amine; Lopac0_000921; ZINC5203; SCHEMBL1322040; AC1L1I31; DTXSID60148871; LZMRVYPPUVMKOI-UHFFFAOYSA-N; N6 -Cyclopentyl-9-Methyl Adenine; N-cyclopentyl-9-methylpurin-6-amine; n0840; BDBM50009698; CCG-205003; NCGC00094232-01; NCGC00015717-03; NCGC00094232-03; NCGC00015717-02; NCGC00015717-01
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H15N5
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| Canonical SMILES |
CN1C=NC2=C(N=CN=C21)NC3CCCC3
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| InChI |
1S/C11H15N5/c1-16-7-14-9-10(12-6-13-11(9)16)15-8-4-2-3-5-8/h6-8H,2-5H2,1H3,(H,12,13,15)
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| InChIKey |
LZMRVYPPUVMKOI-UHFFFAOYSA-N
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| CAS Number |
CAS 109292-91-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A1 receptor (ADORA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cGMP-PKG signaling pathway | |||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Morphine addiction | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| RANKL Signaling Pathway | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor. J Med Chem. 1991 Sep;34(9):2877-82. | |||
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