Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01JUF
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| Former ID |
DAP000299
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| Drug Name |
Phentolamine
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| Synonyms |
Dibasin; Fentolamin; Fentolamina; Phenotolamine; Phentalamine; Phentolaminum; Regitin; Regitine; Regitipe; Regityn; Rogitine; Phentolamine mesylate [USAN]; Phentolamine methanesulfonate; C 7337; C 7337 Ciba; Fentolamina [INN-Spanish]; Phentolamine (INN); Phentolamine [INN:BAN]; Phentolamine, methyl sulfonate; Phentolaminum [INN-Latin]; Vasomax (TN); 2-((N-(m-Hydroxyphenyl)-p-toluidino)methyl)-2-imidazoline; 2-(N'-p-Tolyl-N'-m-hydroxyphenylaminomethyl)-2-imidazoline; 2-(N-(m-Hydroxyphenyl)-p-toluidinomethyl)imidazoline; 2-(m-Hydroxy-N-p-tolylanilinomethyl)-2-imidazoline; 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol; 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol
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| Drug Type |
Small molecular drug
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| Indication | Dermal necrosis [ICD-11: MC85; ICD-10: K05] | Approved | [1], [2] | |
| Therapeutic Class |
Antihypertensive Agents
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| Company |
Bedford Laboratories
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H19N3O
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| Canonical SMILES |
CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O
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| InChI |
1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
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| InChIKey |
MRBDMNSDAVCSSF-UHFFFAOYSA-N
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| CAS Number |
CAS 50-60-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
840956, 860967, 3249474, 5136946, 7980295, 8153547, 11112200, 11335982, 11361221, 11362891, 11365453, 11368015, 11371816, 11374477, 11376177, 11462193, 11466258, 11467378, 11485936, 11490604, 11492714, 11493891, 14848762, 26751465, 26751466, 26751467, 29224810, 46506535, 47424187, 47573329, 47573330, 47720558, 47720559, 47720560, 48018848, 48094496, 48094497, 48169316, 48169317, 48416421, 49698396, 50005392, 50085867, 50100389, 50100390, 50103967, 50103968, 50737406, 53786858, 57322944
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| ChEBI ID |
CHEBI:8081
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| ADReCS Drug ID | BADD_D01758 ; BADD_D01759 | |||
| SuperDrug ATC ID |
C04AB01; V03AB36
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| SuperDrug CAS ID |
cas=000050602
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 502). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040235. | |||
| REF 3 | Nesfatin-1 exerts cardiovascular actions in brain: possible interaction with the central melanocortin system. Am J Physiol Regul Integr Comp Physiol. 2009 Aug;297(2):R330-6. | |||
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