Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D01JZO
|
|||
Former ID |
DNC013088
|
|||
Drug Name |
1-(4-chlorobenzyl)-1H-imidazole
|
|||
Synonyms |
1-(4-chlorobenzyl)-1H-imidazole; 42032-27-9; CHEMBL441367; 1-[(4-chlorophenyl)methyl]imidazole; chlorbenzyl imidazole; AC1MCUZ8; 1H-Imidazole, 1-[(4-chlorophenyl)methyl]-; 1-(p-chlorobenzyl)imidazole; 1-(4-Chlorobenzyl)imidazole; SCHEMBL570342; CTK6H0128; MolPort-001-764-407; RPLWYOLCHGTNSX-UHFFFAOYSA-N; ZINC161401; BDBM50188097; AKOS002677375; MCULE-5157261929
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C10H9ClN2
|
|||
Canonical SMILES |
C1=CC(=CC=C1CN2C=CN=C2)Cl
|
|||
InChI |
1S/C10H9ClN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2
|
|||
InChIKey |
RPLWYOLCHGTNSX-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Androgen biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
Prolactin signaling pathway | ||||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Steroidogenesis | ||||
Reactome | Androgen biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Steroid Biosynthesis | ||||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Glucocorticoid & Mineralcorticoid Metabolism | ||||
Prostate Cancer | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitor... Bioorg Med Chem Lett. 2006 Sep 15;16(18):4752-6. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.