Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01LUJ
|
|||
| Drug Name |
PMID27376512-Compound-Figure2aExample1
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED HENDRICKSON, Thomas, Francis HO, Koc-Kan SAUNDERS, Michael, David STEVENS, Brian, John SWIERCZEK, Krzysztof WRIGHT, Kevin, Bret
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C16H19ClN8O3S
|
|||
| Canonical SMILES |
C1=CN=C(N=C1Cl)NCCSCC2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)O
|
|||
| InChI |
1S/C16H19ClN8O3S/c17-9-1-2-19-16(24-9)20-3-4-29-5-8-11(26)12(27)15(28-8)25-7-23-10-13(18)21-6-22-14(10)25/h1-2,6-8,11-12,15,26-27H,3-5H2,(H2,18,21,22)(H,19,20,24)/t8-,11-,12-,15-/m0/s1
|
|||
| InChIKey |
ZWBSJRQJKXXDKA-REXDEQPNSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA [cytosine-5]-methyltransferase 3-like (DNMT3L) | Target Info | Inhibitor | [1] |
| DNA [cytosine-5]-methyltransferase 3A (DNMT3A) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | DNA [cytosine-5]-methyltransferase 3-like (DNMT3L) | Target's Patent Info | [1] | |
| DNA [cytosine-5]-methyltransferase 3A (DNMT3A) | Target's Patent Info | [1] | ||
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Metabolic pathways | ||||
| MicroRNAs in cancer | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DNA methyltransferase inhibitors: an updated patent review (2012-2015).Expert Opin Ther Pat. 2016 Sep;26(9):1017-30. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.