Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01SQY
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| Former ID |
DNC012402
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| Drug Name |
TZI-41127
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| Synonyms |
Tzi-41127; 104007-80-9; 2-(4-Hydroxy-3,5-dimethylphenyl)-5-methoxy-3-methylindole; CHEMBL76586; Phenol,4-(5-methoxy-3-methyl-1H-indol-2-yl)-2,6-dimethyl-; OZFHUMGEWVYBRM-UHFFFAOYSA-N; ACMC-1BUG2; AC1L2TV9; SCHEMBL10459430; CTK4A2589; DTXSID20146217; Phenol, 4-(5-methoxy-3-methyl-1H-indol-2-yl)-2,6-dimethyl-; BDBM50283452; 4-(5-methoxy-3-methyl-1H-indol-2-yl)-2,6-dimethylphenol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H19NO2
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| Canonical SMILES |
CC1=CC(=CC(=C1O)C)C2=C(C3=C(N2)C=CC(=C3)OC)C
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| InChI |
1S/C18H19NO2/c1-10-7-13(8-11(2)18(10)20)17-12(3)15-9-14(21-4)5-6-16(15)19-17/h5-9,19-20H,1-4H3
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| InChIKey |
OZFHUMGEWVYBRM-UHFFFAOYSA-N
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| CAS Number |
CAS 104007-80-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Arachidonic acid metabolism | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design of pyrrolo-1,4-benzoxazine derivatives as inhibitors of 5-lipoxygenase and PAF antagonists with anthihistaminic properties, Bioorg. Med. Chem. Lett. 4(20):2383-2388 (1994). | |||
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