Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01VNL
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| Former ID |
DIB012441
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| Drug Name |
JM-1232(-)
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| Synonyms |
Sedative, Maruishi; Benzodiazepine agonist (sedation), Maruishi
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Investigative | [1] | |
| Company |
Maruishi Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C24H27N3O2
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| Canonical SMILES |
CN1CCN(CC1)C(=O)CC2C3=C(C=C4CCCC4=C3)C(=O)N2C5=CC=CC=C5
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| InChI |
1S/C24H27N3O2/c1-25-10-12-26(13-11-25)23(28)16-22-20-14-17-6-5-7-18(17)15-21(20)24(29)27(22)19-8-3-2-4-9-19/h2-4,8-9,14-15,22H,5-7,10-13,16H2,1H3/t22-/m1/s1
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| InChIKey |
MBGOHVUPIPFVMM-JOCHJYFZSA-N
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| CAS Number |
CAS 1013427-48-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor gamma-3 (GABRG3) | Target Info | Agonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415). | |||
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