Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02EPZ
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| Former ID |
DNC005056
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| Drug Name |
2-(2,6-Dimethyl-benzyl)-4,5-dihydro-1H-imidazole
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| Synonyms |
CHEMBL71033; SCHEMBL953521; 2-(2,6-Dimethyl-benzyl)-4,5-dihydro-1H-imidazole; 1H-Imidazole, 2-[(2,6-dimethylphenyl)methyl]-4,5-dihydro-; BDBM50064817; 2-(2,6-Dimethylbenzyl)-2-imidazoline
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H16N2
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| Canonical SMILES |
CC1=C(C(=CC=C1)C)CC2=NCCN2
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| InChI |
1S/C12H16N2/c1-9-4-3-5-10(2)11(9)8-12-13-6-7-14-12/h3-5H,6-8H2,1-2H3,(H,13,14)
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| InChIKey |
GPUVYOKQAJEFBO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4697-9. | |||
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