Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02HTG
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| Former ID |
DNC013094
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| Drug Name |
1-(3,5-difluorobenzyl)-1H-imidazole
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| Synonyms |
1-(3,5-difluorobenzyl)-1H-imidazole; CHEMBL446946; 170166-01-5; SCHEMBL10518956; CTK0E4909; DTXSID20474067; 1-(3,5-Difluorobenzyl)imidazole; ZINC36466875; BDBM50188089; AKOS027391623; 1-[(3,5-difluorophenyl)methyl]-1H-imidazole; 1H-Imidazole, 1-[(3,5-difluorophenyl)methyl]-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H8F2N2
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| Canonical SMILES |
C1=CN(C=N1)CC2=CC(=CC(=C2)F)F
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| InChI |
1S/C10H8F2N2/c11-9-3-8(4-10(12)5-9)6-14-2-1-13-7-14/h1-5,7H,6H2
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| InChIKey |
HGEAQRQBZSYPGD-UHFFFAOYSA-N
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| CAS Number |
CAS 170166-01-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Steroidogenesis | ||||
| Reactome | Androgen biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Steroid Biosynthesis | ||||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| Prostate Cancer | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hy... Bioorg Med Chem Lett. 2006 Aug 1;16(15):4011-5. | |||
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