Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02NED
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| Former ID |
DNC010750
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| Drug Name |
NSC-637991
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| Synonyms |
CCRIS 7538; NSC-637991; 5-((2-(Dimethylamino)ethyl)amino)-8-hydroxy-1-methyl-6H-imidazo(4,5,1-de)acridin-6-one; CHEMBL124373; 138154-38-8; AC1L4CDI; DTXSID50160507; ZINC5116458; BDBM50008352; NCI60_012640; LS-189185; 5-(2-(dimethylamino)ethylamino)-8-hydroxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H20N4O2
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| Canonical SMILES |
CC1=NC2=C3N1C4=C(C=C(C=C4)O)C(=O)C3=C(C=C2)NCCN(C)C
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| InChI |
1S/C19H20N4O2/c1-11-21-15-6-5-14(20-8-9-22(2)3)17-18(15)23(11)16-7-4-12(24)10-13(16)19(17)25/h4-7,10,20,24H,8-9H2,1-3H3
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| InChIKey |
RWGHRNQPAMSGPF-UHFFFAOYSA-N
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| CAS Number |
CAS 138154-38-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Quinone reductase 2 (NQO2) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Imidazoacridin-6-ones as novel inhibitors of the quinone oxidoreductase NQO2. Bioorg Med Chem Lett. 2010 May 1;20(9):2832-6. | |||
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