Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02PLD
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| Former ID |
DNC011895
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| Drug Name |
1-(2-Butoxy-phenyl)-piperazine
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| Synonyms |
CHEMBL9452; Piperazine, 1-(2-butoxyphenyl)-; 106476-37-3; 1-(2-Butoxy-phenyl)-piperazine; ACMC-20ma64; 1-(2-Butoxyphenyl)piperazine; SCHEMBL9319475; CTK0G3319; DTXSID60560817; ZINC25997855; BDBM50017460
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H22N2O
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| Canonical SMILES |
CCCCOC1=CC=CC=C1N2CCNCC2
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| InChI |
1S/C14H22N2O/c1-2-3-12-17-14-7-5-4-6-13(14)16-10-8-15-9-11-16/h4-7,15H,2-3,8-12H2,1H3
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| InChIKey |
YNPHKRWUIFAKLL-UHFFFAOYSA-N
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| CAS Number |
CAS 106476-37-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
| 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. J Med Chem. 1989 May;32(5):1052-6. | |||
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