Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02XMQ
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| Former ID |
DNC010366
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| Drug Name |
1-amino-4-methoxyanthracene-9,10-dione
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| Synonyms |
1-Amino-4-methoxyanthraquinone; 1-amino-4-methoxyanthracene-9,10-dione; 116-83-6; 4-Methoxy-1-anthraquinonylamine; 1-Amino-4-methoxy-9,10-anthraquinone; UNII-BCH9T82ZKZ; NSC 84162; BCH9T82ZKZ; BRN 2218945; ANTHRAQUINONE, 1-AMINO-4-METHOXY-; CHEMBL600008; 9,10-Anthracenedione, 1-amino-4-methoxy- (9CI); NSC84162; AC1L1QQQ; cid_8321; 9, 1-amino-4-methoxy-; MLS000585344; 1-Methoxy-4-aminoanthraquinone; SCHEMBL2303569; CTK4A9995; DTXSID40151262; KXOGXZAXERYOTC-UHFFFAOYSA-N; HMS2536C23; ZINC3874026; NSC-84162; BDBM50306771; AKOS001666411
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H11NO3
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| Canonical SMILES |
COC1=C2C(=C(C=C1)N)C(=O)C3=CC=CC=C3C2=O
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| InChI |
1S/C15H11NO3/c1-19-11-7-6-10(16)12-13(11)15(18)9-5-3-2-4-8(9)14(12)17/h2-7H,16H2,1H3
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| InChIKey |
KXOGXZAXERYOTC-UHFFFAOYSA-N
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| CAS Number |
CAS 116-83-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A2a receptor (ADORA2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Rap1 signaling pathway | |||
| Calcium signaling pathway | ||||
| cAMP signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Vascular smooth muscle contraction | ||||
| Parkinson's disease | ||||
| Alcoholism | ||||
| Pathwhiz Pathway | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | |||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Reactome | NGF-independant TRKA activation | |||
| Adenosine P1 receptors | ||||
| G alpha (s) signalling events | ||||
| Surfactant metabolism | ||||
| WikiPathways | Nucleotide GPCRs | |||
| Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| NGF signalling via TRKA from the plasma membrane | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem. 2010 Feb 25;53(4):1799-809. | |||
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